FDA approves GlaxoSmithKline’s Tivicay, for the treatment of AIDS
August 14, 2013 | By Márcio Barra
GSK announced yesterday that the FDA has given green light for ViiV Healthcare’s Tivicay(dolutegravir) 50-mg tablets, an integrase inhibitor indicated for use in combination with other antiretroviral agents for the treatment of HIV-1 in adults and children aged 12 years and older weighing at least 40 kg (approx. 88 lbs). It can be used to treat infected adults who have been treated with other drugs or are new to treatment.
Integrase inhibitors are a new class of antiretroviral agents that block HIV replication in the body by preventing the viral DNA from integrating into the genetic material of human immune cells (T-cells). In short, they stop the virus from entering cells.
In the SINGLE trial, 88% of study participants on the Tivicay regimen were virologically suppressed versus 81% taking Atripla (efavirenz/emtricitabine/tenofovir) after 48 weeks’ treatment.
Tivicay is an add-on to two standard HIV drugs, Ziagen (abacavir) and Zeffix (lamavidune), both available as generics. Tivicay’s wholesale price will be $1,175 per month, or $14,105 per year, a price that has come under fire from Médecins Sans Frontières (MSF).
“We are deeply concerned that ViiV’s business strategy will result in dolutegravir being priced out of reach in countries excluded from ViiV’s licensing deals,” MSF’s Rohit Malpani said in a statement regarding Tivicay’s cost.
A spokesperson for ViiV commented to PharmaTimes that the company is “committed to helping patients receive access to effective HIV treatment in the US and across the globe”.
Tivicay is owned by ViiV Healthcare, an HIV joint venture between GSK, Pfizer, and Shionogi & Co Ltd in which GSK is the largest shareholder, with a 76.5% stake.
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I can believe is possible
that HIV can be cure what
a great man he have done
it for me also I never
believe all this comment
and post about him, I was very sick, I am HIV
positive over 9year,just
last year I keep reading
the testimony post about
this man named DROBI
they said that the man is so powerful he have cured to
different diseases, I keep
monitor the post of some
people about this man and
I found out this man is real
I contacted him for help because I was having such
problem this man reply to
my email after some
hours, I inform he about
my problem that I have
this virus for 9year now this man said that I should
not worry and I should not
disappoint him, what he
about to do for me now is
just a gift from his gods
and his father’s that I s should regard him if am
cured I should write the
true about him, I said no
problem because I never
have the believe that I will
be cured someday but thanks god for my life for
curing me through this
man this man ask for my
details which i send for
him, and he said that he
want to have some consultation on it how to
get me cure I wait for his
respond this man reply me
back after some minute he
said that I need to provide
so thing need for the curing I try and do so after
everything is done I found
out I was again my
strength back my tissue
start developing he ask me
to go for hospital test I did and I found out there was
no HIV found in my body
again what a miracle
thanks doctor for help me
out from this illness i will
continue doing this according to my promise if
you need his help just
contact him now through
his email or phone
number: DROBI6997@GMAIL.COM. OR +23408104071425
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across a comment dr uroko that he have cure to any disease and virus
but when I saw it i have it in mind that he can’t cure HIV I just
decided to give a try I contact him that night lucky to me he said yes
but I don’t believe him I think it was a scam or some thing like that
but I still hold on to see the work of dr uroko if he is saying the
true he ask for different thing and some question about me I give him
all the detail he needed and I wait to see his reply to my problem
after all the thing is done he ask me to go for check up I went for
hiv test I cant believe I was negative thanks dr uroko for help me
for not dying at this young age if you need help contact him now
drurokospellcaster@gmail.com
hello everyone,
i don’t just know the reason why some people is finding it difficult to believe that there is a cure for HIV, i have been HIV+ since last three years with my girlfriend but today i am happy that i am HIV_ with herbal medicine of Dr uroko the great healer,i was browsing the internet searching for help when i came across a testimony shared by someone on how Dr uroko cure his HIV i was so much in need of getting his treatment but after all Dr uroko brought a smile to my face with his herbal medicine. i am so much happy today that we have someone like this great healer out there, so my people out there kindly contact this great heal;er on his email address: drurokospellcaster@gmailco please sir keep your good work cause there are people out there who is in need of your healing medicine.once more contact him now: drurokospellcaster@gmail.com
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I want to say hello to the world at large, I am very grateful for the good deeds DR. AIRHOHO did for me, I was a HIV patient, everything went bad for me, I couldn’t do things with my friends anymore, I loosed my job, I loosed everything, I was even waiting for death itself, I went searching on the internet I saw many testimonies on how different spell casters helped people in curing their deadly diseases, I collected one spell caster’s email, which DR. AIRHOHO I emailed him and he answered me, I told him all problems, he ask me not to worry, that I will be free from the deadly disease, which I did, he casted the spell, and told me that he will send a holy water to me through courier services, I was surprised, because he did not mention it to me before, I paid for the courier delivery service, I got a holy water, he asked me to drink it which I did and he asked me to go for a medical check-up in a hospital, I went to the hospital I went for a HIV test, I was tested HIV negative, I was shocked, I asked myself, “is there still good helpers out there”? I promised to share my testimony to the whole world, I’m now free, I have a better job, if you are passing through pains you need help you can share your problems to DR. AIRHOHO through airhohobreezspellcaster@gmail.com +2348155166695
Truthfully, i was tested HIV + positive last 3years. I keep on managing the drugs i usually purchase from the health care agency to keep me healthy and strenghtful, i tried all i can too make this disease leave me alone, but unfortunately, it keep on eating up my life, this is what i caused myself, for allowing my fiance make sex to me insecurely without protection, although i never knew he is HIV positive. So last few 4days i came in contact with a lively article on the internet on how this Powerful Herb Healer get her well and healed. So as a patient i knew this will took my life 1 day, and i need to live with other friends and relatives too. So i copied out the Dr ihunde the traditional healer’s email id: dr.ihundehivaidscure@yahoo.com and I mailed him immediately, in a little while he mail me back that i was welcome to his temple home were by all what i seek for are granted. I was please at that time. And i continue with him, he took some few details from me and told me that he shall get back to me as soon as he is through with my work. I was very happy as heard that from him. So Yesterday, as i was just coming from my friends house, Dr ihunde called me to go for checkup in the hospital and see his marvelous work that it is now HIV negative, i was very glad to hear that from him, so i quickly rush down to the nearest hospital to found out, only to hear from my hospital doctor called Browning Lewis that i am now HIV NEGATIVE. I jump up at him with the test note, he ask me how does it happen and i recede to him all i went through with Dr ihunde I am now glad, so i am a gentle type of person that need to share this testimonies to everyone who seek for healing, because once you get calm and quiet, so the disease get to finish your life off. So i will advice you contact him today for your healing at the above details: Email ID:dr.ihundehivaidscure@yahoo.com CONTACT HIM NOW TO SAVE YOUR LIFE:dr.ihundehivaidscure@yahoo.com AS HE IS SO POWERFUL AND HELPFUL TO ALL THAT HAVE THIS SICKNESS
I am MRS ELENA HOMSON from RUSSIA, my facebook username is enena homson.i want to use this
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i contacted this disease in 2008, i have done all my best to get cured from this disease
but all to no avail until a friend of mine told me about a healing spell dr OVIA on the
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MY LIFE IS BACK, Am so happy to share this testimony on how Dr ADELEKE BELLO, was able to heal me from HIV Disease, well i was detected positive on 23th may 2016, and ever since i have been looking for a way to treat and cure this disease from me, but all ways i try there was no solution, few weeks ago i saw a testimony of some people on how Dr ADELEKE BELLO,,was able to cure them from HIV disease, still on i heard about it on media when a young lady also gave her testimony about this same Dr, well left with no hope i message Dr ADELEKE BELLO,, telling him all my problem, he told me what we where going to do, that he was going to send me a portion which i am going to take, and after which i took this herb portion he sent to me, he told me to go back to the hospital for check up and after i have done that i should come and tell him the good news result, at first when i saw the message i was so shock and still did not believed i will be cured, well friend to make my story short i am HIV negative now after many time of sorrow, i am Negative, and my sickness are gone, i thank God for leading me to this man….you can email him on (DR.ADELEKEAYODELE1960@GMAIL.COM) or you can also call him +2349035594773 he can be of help to you on any problem like
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